Overall, the Food Directorate's comprehensive review of the available science of TiO₂ as a food additive showed:

Titanium dioxide particles help light scatter and reflect, Kelly Johnson-Arbor, MD, a medical toxicology physician at the National Capital Poison Center, told Health. Because of that, we often use it as a whitening agent.

We even use titanium dioxide when brushing our teeth as it’s found in many toothpastes. 

Lithopone, a white pigment composed of a mixture of barium sulfate and zinc sulfide, is commonly used in the leather industry as a coloring agent. Leather suppliers around the world rely on lithopone to achieve the desired color and finish on their products.