As for titanium dioxide, the FDA approved titanium dioxide for use as a food additive in 1966. The last time the agency reviewed the additive’s safety, according to the Guardian, was in 1973.

Other experts say there is simply no conclusive evidence at this point that titanium dioxide is damaging to humans after ingesting. Kaminski in particular said the research studies cite health hazards that were found by using high doses of the product, which you would not normally see in food.