For a mini-review published in the journal Particle and Fibre Technology in 2021, scientists wanted to evaluate whether Ti02 particles contributed to the development and/or exacerbation of irritable bowel disease, and whether they altered the four elements of intestinal barrier function: the intestinal microbiota, the immune system, the mucus layer, and the epithelium. The breakdown of these four elements can contribute to autoimmune, neurological, inflammatory, infectious, and metabolic diseases. Following their review, the researchers concluded: “Data indicate that TiO2 is able to alter the four compartments of IBF and to induce a low-grade intestinal inflammation associated or not with pre-neoplastic lesions.” 

Moreover, titanium dioxide is also used in rubber formulations to improve the processing and curing properties of rubber compounds. It acts as a catalyst in the vulcanization process, speeding up the cross-linking of rubber molecules and enhancing the overall performance of the final product. This results in rubber products that are stronger, more flexible, and better suited for a wide range of applications.

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