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Despite the global economic fluctuations, China's titanium dioxide industry, especially the R996 segment, has shown remarkable resilience. The continuous innovation and technological upgrades have allowed the sector to maintain its leading position in the international market. As the demand for high-quality pigments continues to rise, China's R996 titanium dioxide is poised to play an increasingly significant role in meeting these demands.

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A few non-dietary studies have reported adverse effects in the gastrointestinal tract of laboratory animals given food-grade TiO2. However, these same effects were not seen when the same or higher doses of food-grade TiO2 were administered in the animals' diet. Dietary studies best reflect how humans are exposed to TiO2 from food. Thus, the Food Directorate placed the most emphasis on the results of these studies in the state of the science report.

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