types of titanium dioxide manufacturer

In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

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Furthermore, titanium dioxide imparts excellent brightness and opacity to plastics, which is crucial for achieving a consistent, high-quality appearance. It helps to mask any impurities or irregularities within the plastic material, resulting in a more attractive and marketable product. For example, in the production of white or light-colored plastic goods like appliances, packaging materials, and toys, TiO2 ensures an even, lustrous finish that consumers find appealing.

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