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One of the main applications of titanium dioxide in paper is in the production of high-quality coated papers. Titanium dioxide is often added to the coating formulations to enhance the whiteness and brightness of the paper surface. This helps to improve the print quality of the paper, as it provides a smooth and even surface for ink to adhere to. The high opacity of titanium dioxide also helps to prevent show-through, making the printed text or images more vibrant and legible.

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In addition to sunscreen, titanium IV oxide is also used in the production of paints. Titanium dioxide is a popular pigment in the paint industry because of its brightness and opacity. It provides excellent coverage and durability, making it an ideal choice for exterior and interior paints. Titanium dioxide is often used in white paints, but it can also be used to create a wide range of colors by mixing it with other pigments.


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The author thanks Marco Leona, Scientist-in-Charge of the Department of Scientific Research at the Metropolitan Museum of Art for conducting fluorescence spectrometry on Wheel of Fortune and a valuable discussion of the research, as well as Silvia Centeno, Research Scientist at the Metropolitan Museum of Art, who performed Raman analysis on the watercolors and also contributed her insight. The phenomenon of the phosphorescing lithopone was originally discovered during the author's fellowship in the Sherman Fairchild Center for the Conservation of Works on Paper, funded by the Andrew W. Mellon Foundation. The author thanks all her colleagues for their ideas and support during the research of this paper, and special thanks to Rachel Mustalish for her assistance in editing this work.

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The first commercial production of TiO2 began in the early 20th century, using the sulfate process. This method involved reacting ilmenite ore with sulfuric acid to produce titanium sulfate, which was then calcined to obtain titanium dioxide. However, this process had several drawbacks, including high energy consumption, generation of large amounts of waste, and release of harmful gases such as sulfur dioxide. As a result, many factories transitioned to the chloride process, which offers higher purity TiO2 and reduced environmental impact.

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For a mini-review published in the journal Particle and Fibre Technology in 2021, scientists wanted to evaluate whether Ti02 particles contributed to the development and/or exacerbation of irritable bowel disease, and whether they altered the four elements of intestinal barrier function: the intestinal microbiota, the immune system, the mucus layer, and the epithelium. The breakdown of these four elements can contribute to autoimmune, neurological, inflammatory, infectious, and metabolic diseases. Following their review, the researchers concluded: “Data indicate that TiO2 is able to alter the four compartments of IBF and to induce a low-grade intestinal inflammation associated or not with pre-neoplastic lesions.” 

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