Overall, r 996 titanium dioxide suppliers have established themselves as reliable and reputable sources for this essential pigment. With their high-quality products, reliable supply chain, competitive pricing, and excellent customer service, businesses can rely on these suppliers for all their r 996 titanium dioxide needs. Partnering with r 996 titanium dioxide suppliers is a smart choice for businesses looking to enhance their production processes and deliver top-quality products to their customers.

Genotoxicity and cytotoxicity 

With a specially designed inorganic surface coating treatment, R-895 excels in weather resistance, making it flexible for use in various indoor and outdoor applications.

In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”