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The author thanks Marco Leona, Scientist-in-Charge of the Department of Scientific Research at the Metropolitan Museum of Art for conducting fluorescence spectrometry on Wheel of Fortune and a valuable discussion of the research, as well as Silvia Centeno, Research Scientist at the Metropolitan Museum of Art, who performed Raman analysis on the watercolors and also contributed her insight. The phenomenon of the phosphorescing lithopone was originally discovered during the author's fellowship in the Sherman Fairchild Center for the Conservation of Works on Paper, funded by the Andrew W. Mellon Foundation. The author thanks all her colleagues for their ideas and support during the research of this paper, and special thanks to Rachel Mustalish for her assistance in editing this work.

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However, the production process of lithopone was not without its challenges. The manufacturing process involved handling hazardous chemicals and generating toxic waste, posing significant health and environmental risks. To address these concerns, factories implemented strict safety measures and invested in research to develop cleaner production methods. These efforts led to the development of new techniques that reduced waste and improved worker safety.

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Despite the various factors that can influence the cost of titanium dioxide, suppliers strive to provide a consistent and reliable supply of this important material to their customers. By investing in research and development, suppliers can improve their production processes and find more cost-effective ways to produce titanium dioxide. This can help to stabilize the cost of titanium dioxide and ensure a steady supply for customers in the future.

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TiO2 comes in many different forms. However, only a few of these forms are considered food-grade (acceptable to be added to food). Many studies that raised concern about the safety of TiO2, including the concern for genotoxicity, used forms of TiO2 that are not considered acceptable for use in food and have different properties than food-grade TiO2. Other studies did use food-grade TiO2, but took steps to break the material down into smaller particles than what would normally be found in food.

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