ponceau 4r and titanium dioxide supplier

Anatase Titanium Dioxide, a form of titanium dioxide (TiO2), is a highly valued substance due to its exceptional optical properties, high refractive index, and strong UV resistance. It is widely employed as a food additive, approved by international regulatory bodies for its safety and efficacy. This article delves into the significance of anatase TiO2 in the food industry and introduces some prominent food grade anatase titanium dioxide suppliers.

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In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”

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