r104 tio2

The demand for 30-50nm TiO2 powders stems from their enhanced surface area to volume ratio, which amplifies their reactivity and photocatalytic efficiency. This attribute is paramount in applications such as photovoltaics, where these nanoparticles can boost energy conversion rates in solar cells. In the field of environmental remediation, they serve as potent catalysts for degrading pollutants under light exposure. Furthermore, the exceptional transparency and refractive index of TiO2 nanoparticles make them ideal for high-performance coatings and paints, offering improved durability and aesthetic appeal.

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In a 2017 study published in Scientific Reports, researchers exposed rats to human-relevant levels of E171 to examine the effects of intestinal inflammation and carcinogenesis. They saw that “a 100-day E171 treatment promoted colon microinflammation and initiated preneoplastic lesions while also fostering the growth of aberrant crypt foci in a chemically induced carcinogenesis model.” They continued: “Stimulation of immune cells isolated from Peyer’s Patches [which are clusters of lymphoid follicles found in the intestine] showed a decrease in Thelper (Th)-1 IFN-γ secretion, while splenic Th1/Th17 inflammatory responses sharply increased,” researchers wrote. “A 100-day titanium dioxide treatment promoted colon microinflammation and initiated preneoplastic lesions.” The scientists concluded: “These data should be considered for risk assessments of the susceptibility to Th17-driven autoimmune diseases and to colorectal cancer in humans exposed to TiO2 from dietary sources.”

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