titanium dioxide use factory

No acute effects of nano-sized TiO2 were observed in Danio rerio (zebrafish) embryos. Exposure of rainbow trout to TiO2 NPs triggered lipid peroxidation, influence on the respiratory tract, disturbance in the metabolism of Cu and Zn, induction of intestinal erosion  and accumulation in kidney tissue. Linhua et al. exposed juvenile carp to 100 and 200 mg/ml of particles and TiO2 observed no mortality. However, the fish suffered from oxidative stress and pathological changes in gill and liver. In the infaunal species Arenicola marina, exposure to TiO2 NPs in sediment caused sub-lethal effects including decrease in casting rate and increase in cellular and DNA damage. Aggregated particles were visible in the lumen of the gut, but no uptake through the gut or the skin was observed.

...

In the realm of pigments, titanium dioxide's ability to reflect light across the visible spectrum makes it an ideal candidate for brightening products. It is widely used in paints, plastics, paper, inks, food coloring, and cosmetics. The addition of TiO2 not only enhances the whiteness but also improves the durability and opacity of these materials. Moreover, its non-toxic nature ensures that it can be safely used in products that come into direct contact with humans, such as food colorants and cosmetics.

...
...