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No acute effects of nano-sized TiO2 were observed in Danio rerio (zebrafish) embryos. Exposure of rainbow trout to TiO2 NPs triggered lipid peroxidation, influence on the respiratory tract, disturbance in the metabolism of Cu and Zn, induction of intestinal erosion  and accumulation in kidney tissue. Linhua et al. exposed juvenile carp to 100 and 200 mg/ml of particles and TiO2 observed no mortality. However, the fish suffered from oxidative stress and pathological changes in gill and liver. In the infaunal species Arenicola marina, exposure to TiO2 NPs in sediment caused sub-lethal effects including decrease in casting rate and increase in cellular and DNA damage. Aggregated particles were visible in the lumen of the gut, but no uptake through the gut or the skin was observed.

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According to the feedback of manufacturers, the recent mainstream factory new single price, the market as a whole into the center of gravity. On the demand side, the terminal in August is still the off-season, many downstream still have inventory use, the current batch purchase intention is limited, and the market turnover is low. Some plastics and papermaking related downstream feedback part of the signal price is high. Recent titanium dioxide raw material price shock is strong, titanium dioxide price upward support has been enhanced, comprehensive market factors, the current titanium dioxide market into the stable price state after rising.

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