titanium dioxide dissolved in oil

In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

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CSPI’s Chemical Cuisine is the web’s definitive rating of the chemicals used to preserve foods and affect their taste, texture, or appearance. Besides titanium dioxide, the group recommends avoiding artificial sweeteners like aspartame, acesulfame potassium, and sucralose, as well as synthetic food dyes like Yellow 5 and Red 3. CSPI and others have recently asked the Food and Drug Administration to ban the latter dye in foods and ingested drugs because the FDA has already determined that it is a carcinogen unsafe for use in cosmetics.

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Below are selected applications of photocatalytic pollutant decomposition processes on titanium oxide:
1. Self-cleaning surfaces: for the production of glass for spotlights, traffic lights, car mirrors, window panes, for road paints, for covering sound-absorbing screens and tunnel walls.
2. Air cleaning and odor removal: filters that are used in enclosed spaces (e.g. public toilets) or filters for air-conditioning equipment.
3. Water treatment: groundwater treatment installations, water purification installations in the intakes of drinking water from rivers.
4. Self-disinfecting materials: towels, linings, clothing, equipment in hospitals, wall surfaces of operating rooms.
5. Removal of lesions: anti-cancer therapy.

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