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In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.” 

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In conclusion, coating raw material manufacturers are not just suppliers; they are partners in progress, shaping the future of various industries through their products. Their work is instrumental in improving efficiency, enhancing durability, and fostering sustainable practices. As technology continues to evolve, we can expect these manufacturers to play an even more pivotal role in creating smarter, more sustainable coatings for tomorrow's world.

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