Lithopone, white powder, relative density: 4.136 ~ 4.39 g / mL, insoluble in water. It is a mixture of zinc sulfide and barium sulfate. Inorganic white pigment, widely used in plastics such as polyolefin, vinyl resin, ABS resin, polystyrene, polycarbonate, nylon and polyoxymethylene, and white pigments of paints and inks. It is less effective in polyurethane and amino resins and less suitable in fluoroplastics. It is also used for coloring of rubber products, paper, varnish, tarpaulin, leather, watercolor paint, paper, enamel, and the like. Used as a binder in the production of electric beads.

The most significant uncertainty identified by the EU experts was the concern that TiO₂ particles may have genotoxic effects. Genotoxicity refers to the ability of a chemical to directly damage genetic material within a cell (DNA), which may lead to cancer in certain situations. Although the experts did not conclude that TiO₂ particles in E171 are genotoxic, they could not rule out the concern that they might be.

Titanium dioxide is a widely used substance in various industries due to its versatility and unique properties. As a result, there are numerous manufacturers of titanium dioxide around the world, catering to the different needs of their customers.