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Hitox and Tio2 are two terms that could potentially refer to brand names or specific types of titanium dioxide products within the industry. While Hitox does not directly correspond to a well-known manufacturer or product line in the TiO2 sector, Tio2 might be seen as an abbreviated form of titanium dioxide. However, it's crucial to note that there are numerous manufacturers of titanium dioxide worldwide, each offering different grades and specialized forms of TiO2 tailored to meet diverse industrial needs.

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White titanium dioxide, commonly known as TiO2, is a vital pigment in various industries due to its exceptional optical properties, including high opacity and whiteness. The manufacturing of this essential compound is predominantly carried out in specialized facilities, known as white titanium dioxide factories. These state-of-the-art factories are not just centers of production; they are also hubs of technological innovation and environmental responsibility.

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For research published in Archives of Toxicology in 2020, scientists fed one group of mice a solution containing titanium dioxide for one month, and compared it to those that did not receive the additive. They found “the richness and evenness of gut microbiota were remarkably decreased and the gut microbial community compositions were significantly changed” in the titanium dioxide group when compared with the control group. The tests also revealed that the titanium dioxide exposure could cause locomotor dysfunction, or mobility issues “by elevating the excitement of enteric neurons, which might spread to the brain via gut-brain communication by vagal pathway.” The researchers concluded: “These findings provide valuable insights into the novel mechanism of TiO2NP-induced neurotoxicity. Understanding the microbiota-gut-brain axis will provide the foundation for potential therapeutic or prevention approaches against TiO2NP-induced gut and brain-related disorders.”

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