china use of lithopone

In an early study Jani et al. administred rutile TiO2 (500 nm) as a 0.1 ml of 2.5 % w/v suspension (12.5 mg/kg BW) to female Sprague Dawley rats, by oral gavage daily for 10 days and detected presence of particles in all the major gut associated lymphoid tissue as well as in distant organs such as the liver, spleen, lung and peritoneal tissue, but not in heart and kidney. The distribution and toxicity of nano- (25 nm, 80 nm) and submicron-sized (155 nm) TiO2 particles were evaluated in mice administered a large, single, oral dosing (5 g/kg BW) by gavage. In the animals that were sacrificed two weeks later, ICP-MS analysis showed that the particles were retained mainly in liver, spleen, kidney, and lung tissues, indicating that they can be transported to other tissues and organs after uptake by the gastrointestinal tract. Interestingly, although an extremely high dose was administrated, no acute toxicity was observed. In groups exposed to 80 nm and 155 nm particles, histopathological changes were observed in the liver, kidney and in the brain. The biochemical serum parameters also indicated liver, kidney and cardiovascular damage and were higher in mice treated with nano-sized (25 or 80 nm) TiO2 compared to submicron-sized (155 nm) TiO2. However, the main weaknesses of this study are the use of extremely high single dose and insufficient characterisation of the particles.

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One of the key benefits of using R-906 rutile TiO2 is its ability to improve the overall quality of printed materials. By providing excellent whiteness and opacity, R-906 enhances the visual appeal of printed products, making them more eye-catching and professional-looking. Additionally, the chemical stability of R-906 ensures that printed materials maintain their color and appearance even under harsh environmental conditions, such as high humidity and exposure to sunlight.

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The rise of China's titanium dioxide importers can be attributed to several factors. Firstly, China's rapid industrialization and urbanization have resulted in a surge in construction projects, which require vast amounts of paint and other building materials containing TiO2. Additionally, the country's thriving manufacturing sector, particularly in the production of appliances, furniture, and automobiles, has further driven up the demand for titanium dioxide. As a result, Chinese importers have been scouring the globe for reliable suppliers capable of meeting their extensive requirements.

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  • The Market Dynamics of Wholesale Titanium Dioxide


  • Titanium dioxide, also known as TiO2, is a white pigment that is highly stable and non-toxic. It is commonly used in paints, plastics, papers, and cosmetics due to its excellent brightness and high refractive index. In the paint industry, titanium dioxide is added to enhance the opacity and durability of the product, ensuring long-lasting protection for surfaces. Manufacturers rely on this pigment to produce high-quality paints that meet customer demands for superior performance and aesthetic appeal.