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In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

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Firstly, it's essential to understand what makes lithopone a preferred choice for many consumers. Unlike traditional lead-based paints, lithopone is free from harmful substances, making it an environmentally friendly option. Its superior coverage means that fewer coats are needed to achieve the desired finish, which translates to cost savings for homeowners and contractors alike. Moreover, lithopone's brightness index is higher than most pigments, ensuring a vibrant and long-lasting appearance on walls.

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