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China's titanium oxide industry has also been investing in research and development to improve the quality and performance of their products. By developing new processing techniques and formulations, Chinese manufacturers are able to offer a wide range of titanium oxide products that meet the diverse needs of their customers
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china titanium oxide. This has helped China to establish a strong presence in the global titanium oxide market, competing with other major producers such as the United States, Germany, and Japan.

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In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”

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