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Recently, Yanagisawa et al. reported that the transdermal exposure (mimicking skin-barrier dysfunction or defect) of NC/Nga mice to TiO2 NPs (15, 50, or 100 nm), in combination with allergen, aggravated atopic dermatitis-like lesions through a T-helper type 2 (Th2) dominant immune response. The study also indicated that TiO2 NPs can play a role in the initiation and/or progression of skin diseases, since histamine was released, even in the absence of allergen.

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Likewise, the plastics industry relies heavily on titanium dioxide to enhance the appearance and durability of plastic products. With the increasing popularity of plastic packaging and consumer goods, the demand for titanium dioxide in this industry is expected to witness steady growth in the coming years. The versatility of titanium dioxide makes it a valuable additive to improve the brightness, opacity and color stability of plastic materials, ensuring improved product performance and consumer satisfaction.

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