billions tio2 factories

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The advent of micronized TiO2, also known as titanium dioxide, has revolutionized various industries, from paints and coatings to food coloring and sunscreen lotions. This ultra-fine version of TiO2 boasts enhanced properties such as improved brightness, greater pigment performance, and superior UV protection due to its increased surface area. As the demand for micronized TiO2 grows, factories around the globe have adapted their methodologies to cater to this specialized market.

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In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.” 

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