tinox tio2 manufacturer

For research published in 2022 study in the journal Food and Chemical Toxicology, scientists examined “the genotoxicity and the intracellular reactive oxygen species induction by physiologically relevant concentrations of three different TiO2 nanomaterials in Caco-2 and HT29-MTX-E12 intestinal cells, while considering the potential influence of the digestion process in the NMs’ physiochemical characteristics.” They found a “DNA-damaging effect dependent on the nanomaterial,” along with the micronucleus assay suggesting “effects on chromosomal integrity, an indicator of cancer risk, in the HT29-MTX-E12 cells, for all the tested TiO2 nanomaterials.” Researchers concluded that the results showcase “evidence of concern” regarding titanium dioxide used as a food additive.

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Procurement of TIO2 involves a complex process, starting from sourcing the raw materials, primarily ilmenite, rutile, or titanium-bearing slag, to negotiating contracts with suppliers. Manufacturers often prioritize suppliers that can guarantee consistent quality, competitive pricing, and reliable delivery schedules. This necessitates strong relationships and strategic partnerships with mining companies, which are typically located in regions rich in titanium resources, such as Australia, South Africa, and Canada.

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