Food safety experts in the European Union (EU) have recently updated their safety assessment of TiO₂ as a food additive. In Europe, TiO₂ is referred to as E171, in accordance with European labelling requirements for food additives. The EU expert panel took into account toxicity studies of TiO₂ nanoparticles, which to this point had not been considered relevant to the safety assessment of TiO₂ as a food additive.  

All samples (n = 6) were irradiated in a 96 well plate using an LED panel on top for 3 and 6 h before analysis. An identical set of samples were kept in the dark as controls. The temperature was checked and did not go over 37 °C. The intensity of light was also measured and was constant at 19,500.10 lux. (43.33 W in 0.2 m²), about 5 times less than actual solar light intensity on Earth's surface Therefore, these findings are indicative of even greater danger in real life.

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