titanium dioxide ultra white paint factory

In a 2017 study published in Scientific Reports, researchers exposed rats to human-relevant levels of E171 to examine the effects of intestinal inflammation and carcinogenesis. They saw that “a 100-day E171 treatment promoted colon microinflammation and initiated preneoplastic lesions while also fostering the growth of aberrant crypt foci in a chemically induced carcinogenesis model.” They continued: “Stimulation of immune cells isolated from Peyer’s Patches [which are clusters of lymphoid follicles found in the intestine] showed a decrease in Thelper (Th)-1 IFN-γ secretion, while splenic Th1/Th17 inflammatory responses sharply increased,” researchers wrote. “A 100-day titanium dioxide treatment promoted colon microinflammation and initiated preneoplastic lesions.” The scientists concluded: “These data should be considered for risk assessments of the susceptibility to Th17-driven autoimmune diseases and to colorectal cancer in humans exposed to TiO2 from dietary sources.”

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The production process of lithopone involves a sophisticated synthesis of zinc sulfide and barium sulfate, resulting in a pigment that boasts high whiteness, opacity, and heat stability. The ratio of ZnS to BaSO4 can be adjusted to cater to specific applications, with some formulations containing up to 70% zinc sulfide and 30% barium sulfate. This flexibility makes lithopone an adaptable solution for manufacturers seeking optimal performance in their products.

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