use of titanium dioxide in medicine manufacturers

The gastrointestinal tract is a complex barrier/exchange system, and is the most important route by which macromolecules can enter the body. The main absorption takes place through villi and microvilli of the epithelium of the small and large intestines, which have an overall surface of about 200 m2. Already in 1922, it was recognized by Kumagai, that particles can translocate from the lumen of the intestinal tract via aggregation of intestinal lymphatic tissue (Peyer’s patch, containing M-cells (phagocytic enterocytes)). Uptake can also occur via the normal intestinal enterocytes. Solid particles, once in the sub-mucosal tissue, are able to enter both the lymphatic and blood circulation.

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The refractive index of rutile TiO2 is among the highest known, which results in unparalleled hiding power in paints and coatings. Its ability to reflect light across a broad spectrum enhances the brightness and opacity of products, thereby reducing the amount of pigment required to achieve the desired effect. Consequently, rutile is frequently chosen over other types of TiO2 in industrial applications where high performance and cost efficiency are paramount.

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