competitive price rutile titanium dioxide

The global market for rutile titanium dioxide is competitive, with leading manufacturers continuously striving to improve their production processes and product qualityrutile titanium dioxide manufacturers. Innovations such as nanotechnology have allowed for the creation of nano-sized titanium dioxide particles, enhancing the pigment's performance in terms of opacity, strength, and durability. Moreover, environmental concerns have prompted manufacturers to develop more sustainable production practices, including the use of cleaner technologies and waste reduction strategies.

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In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

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