For research published in 2022 study in the journal Food and Chemical Toxicology, scientists examined “the genotoxicity and the intracellular reactive oxygen species induction by physiologically relevant concentrations of three different TiO2 nanomaterials in Caco-2 and HT29-MTX-E12 intestinal cells, while considering the potential influence of the digestion process in the NMs’ physiochemical characteristics.” They found a “DNA-damaging effect dependent on the nanomaterial,” along with the micronucleus assay suggesting “effects on chromosomal integrity, an indicator of cancer risk, in the HT29-MTX-E12 cells, for all the tested TiO2 nanomaterials.” Researchers concluded that the results showcase “evidence of concern” regarding titanium dioxide used as a food additive.

1.Mainly used in latex paints, water-based paints, inks, rubber, plastics, etc., replacing 30% of rutile-type titanium dioxide in latex paints, still maintaining the original film properties, and has the effect of reducing costs.

Developing new Lithopone formulations, one that enhances the properties of the existing Lithopone is anticipated to boost the demand for Lithopone white pigment during the forecast period. Reinforced Lithopone is one such development, wherein a copolymer is added to the polymerization reaction to yield Lithopone with increased weather resistance. Moreover, development of nano-scale Lithopone is anticipated to attract market interest during the forecast period.