It is a white crystalline powder, which is a mixture of zinc sulfide and barium sulfate. The more zinc sulfide it contains, the stronger the hiding power and the higher the quality. The density of lithopone is 4.136~4.34/cm3 and it is insoluble in water. It easily decomposes when exposed to acid to produce hydrogen sulfide gas, but does not work when exposed to hydrogen sulfide and alkaline solutions.

Duan et al. administered 125 mg/kg BW or 250 mg/kg BW of anatase TiO₂ (5 nm) intragastrically to mice continuously for 30 days. The exposed mice lost body weight, whereas the relative liver, kidney, spleen and thymus weights increased. Particles seriously affected the haemostasis of the blood and the immune system. The decrease in the immune response could be the result of damage to the spleen, which is the largest immune organ in animals and plays an important role in the immune response. Powel et al. demonstrated that TiO₂ NPs may trigger immune reactions of the intestine after oral intake. They showed that TiO₂ NPs conjugated with bacterial lipopolysaccharide, but not TiO₂ NPs or lipopolysaccharide alone, trigger the immune response in human peripheral blood mononuclear cells and in isolated intestinal tissue. This indicates that TiO₂ NPs may be important mediators in overcoming normal gut-cell hyporesponsiveness to endogenous luminal molecules, which may be particularly relevant to patients with inflammatory bowel disease, which is characterized by an abnormal intestinal permeability.

In the manufacturing industry, sometimes many products require coloring, and the ideal coloring material is lithopone. This is a product manufactured through chemical methods. It is a mixture of barium sulfate and zinc sulfide. When the product contains more zinc sulfide, its effect will be better, that is, the coloring ability will be more stable. If you want to buy high-quality lithopone, you have to understand its properties and characteristics. Today’s article will give you a detailed understanding of lithopone.