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For research published in Archives of Toxicology in 2020, scientists fed one group of mice a solution containing titanium dioxide for one month, and compared it to those that did not receive the additive. They found “the richness and evenness of gut microbiota were remarkably decreased and the gut microbial community compositions were significantly changed” in the titanium dioxide group when compared with the control group. The tests also revealed that the titanium dioxide exposure could cause locomotor dysfunction, or mobility issues “by elevating the excitement of enteric neurons, which might spread to the brain via gut-brain communication by vagal pathway.” The researchers concluded: “These findings provide valuable insights into the novel mechanism of TiO2NP-induced neurotoxicity. Understanding the microbiota-gut-brain axis will provide the foundation for potential therapeutic or prevention approaches against TiO2NP-induced gut and brain-related disorders.”

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Prof Maged Younes, Chair of EFSA’s expert Panel on Food Additives and Flavourings (FAF), said: “Taking into account all available scientific studies and data, the Panel concluded that titanium dioxide can no longer be considered safe as a food additive . A critical element in reaching this conclusion is that we could not exclude genotoxicity concerns after consumption of titanium dioxide particles. After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body”. 

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  • Titanium dioxide (TiO2) is a versatile and widely used compound with a myriad of applications across diverse industries. Its importance is underpinned by the role it plays in sectors ranging from cosmetics to paints, food, and even solar panels. This has led to a thriving market for titanium dioxide suppliers who cater to these demands, ensuring a consistent and high-quality supply of this crucial material.
  • Fourthly, titanium dioxide is also used in cosmetics and personal care products due to its ability to absorb UV radiation and protect the skin from sun damage. It is commonly found in sunscreens, foundations, and other skincare products.
  • In conclusion, titanium dioxide is a versatile and essential ingredient in the wholesale market, with a wide range of applications in various industries. Its unique properties and ever-growing demand make it a valuable commodity for manufacturers and consumers alike. As the demand for sustainable and eco-friendly products continues to grow, the future of titanium dioxide in the wholesale market looks promising.