In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

At the same time, the company took the lead in building a product application testing system in the industry, and formed a relatively complete product application testing system. Among them, the hue of blue-phase R838 titanium dioxide reaches the world-class level. The gloss of R838 titanium dioxide, a silicon-aluminum coated product, has surpassed other domestic silicon-aluminum coated products, and reached or even exceeded some domestic zirconium-aluminum products. Titanium dioxide for color masterbatch is recognized by customers for its high whiteness, high coverage and other indicators, the product market share has been greatly increased, and it enjoys high brand awareness and reputation at home and abroad.

English name: Lithopone