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In a study published in the journal Food and Chemical Toxicology in 2016, researchers investigated whether titanium dioxide exposure led to an increase in colorectal tumor creation in mice by using a colitis associated cancer model. By measuring tumor progression markers, the researchers found that mice given titanium dioxide experienced enhanced tumor formation in the distal colon.  There was also a decrease of cells that act as a protective barrier in the colon. The researchers wrote: “These results suggest that E171 could worsen pre-existent intestinal diseases.”

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The cosmetics sector also heavily relies on TiO2, especially in sunscreens and other skincare products. It provides natural sun protection by blocking harmful UV rays, while its non-toxic nature ensures safe usage on human skin It provides natural sun protection by blocking harmful UV rays, while its non-toxic nature ensures safe usage on human skin It provides natural sun protection by blocking harmful UV rays, while its non-toxic nature ensures safe usage on human skin It provides natural sun protection by blocking harmful UV rays, while its non-toxic nature ensures safe usage on human skinraw material pigment agent cas 13463-67-7 bulk cas 13463-67-7 99% tio2 titanium dioxide powder. Furthermore, in the food industry, titanium dioxide is approved as a food additive, providing color to food products, including confectionery, dairy, and bakery items.

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