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A 2023 study published in the journal Particle and Fibre Toxicology set out to examine the impact of titanium dioxide nanoparticles in mice “on the course and prognosis of ulcerative colitis,” by creating an ulcerative colitis disease model. Researchers found that the titanium dioxide nanoparticles significantly increased the severity of colitis. They also “decreased the body weight, increased the disease activity index and colonic mucosa damage index scores, shortened the colonic length, increased the inflammatory infiltration in the colon.” Researchers concluded: “Oral intake of TiO2 nanoparticles could affect the course of acute colitis in exacerbating the development of ulcerative colitis, prolonging the ulcerative colitis course and inhibiting ulcerative colitis recovery.”

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In conclusion, Anatase Titanium Dioxide plays a significant role in the food industry due to its unique properties as a coloring agent, anti-caking agent, and for preserving the original taste of food products. Its safety profile makes it a reliable choice for manufacturers looking to enhance the appearance and shelf life of their products while ensuring they are safe for consumption. As technology advances and consumer preferences evolve, the use of food-grade titanium dioxide is likely to continue being an integral part of food processing and presentation.

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