cas: 13463-67-7 titanium dioxide powder factories

Australian researchers examined how titanium dioxide as a food additive affected gut microbiota in mice by orally administering it in drinking water. The study, published in the journal Frontiers in Nutrition in 2019, found the treatment could “alter the release of bacterial metabolites in vivo and affect the spatial distribution of commensal bacteria in vitro by promoting biofilm formation. We also found reduced expression of the colonic mucin 2 gene, a key component of the intestinal mucus layer, and increased expression of the beta defensin gene, indicating that titanium dioxide significantly impacts gut homeostasis.” The changes were then linked to colonic inflammation, along with a higher expression of inflammatory cytokines, which are signal proteins that help with regulation. The researchers concluded that titanium dioxide “impairs gut homeostasis which may in turn prime the host for disease development.”

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Moreover, Sachtleben's research and development team continuously explores new frontiers in TiO2 applicationssachtleben tio2 manufacturer. By collaborating with industry experts and investing in scientific research, they have developed specialized TiO2 grades tailored for specific customer needs. These include high-gloss TiO2 for automotive paints, ultra-fine grades for printing inks, and even TiO2 variants designed for use in food and pharmaceuticals, adhering to stringent safety regulations.

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