What titanium dioxide is really emblematic of ... is the failure of FDA to look back at these old decisions and ask whether its decisions that were made in this case ... 56 years ago (in the 1966 approval) still hold up, he said.

Given its widespread use, finding reliable suppliers of barium sulphate is crucial for industries that rely on this compound. Many companies specialize in the production and distribution of barium sulphate, ensuring that businesses can source high-quality materials tailored to their specific needs.

A 2022 review on past studies of titanium dioxide and rat lung cancer, for instance, said the original study was under extreme conditions and its effects were not replicated in other animal species. Additionally, the review concluded that the few studies which did directly focus on titanium dioxide's impact on humans did not end up showing any increased cancer risk.