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In conclusion, titanium dioxide serves as a cornerstone in the production of high-quality interior and exterior wall paint materials. Its unique combination of opacity, weather resistance, safety, and versatility makes it an essential ingredient for achieving optimal paint performance. As technology advances and new applications emerge, the demand for this remarkable pigment is expected to continue growing, solidifying its place in the paint industry for years to come.

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In order to contribute with experimental evidence that could help to achieve a better understanding of the field for future regulation, in the present work, the biocompatibility of commercial P25TiO2NPs (one type of TiO2NPs used in sunscreen formulations) and two novel functionalized P25TiO2NPs were evaluated under solar simulated irradiation. White light, generated by red, blue, and yellow LEDs, together with UV ones, was chosen to simulate the solar spectra. Functionalization of TiO2NPs was made with antioxidant vitamins in order to prevent the expected photo-initiated ROS production when nanoparticles are exposed to the simulated solar spectra. Vitamin B2 (riboflavin) and vitamin C were chosen to carry out the functionalization because they are water-soluble, low-cost, and are a constitutive part of biological processes. In addition, it is known that both have the potential to prevent macromolecular oxidation by ROS [23][24][25][26].

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In conclusion, TIO2 procurement and manufacturing is a dynamic sector that continually adapts to changing market dynamics, technological innovations, and environmental considerations. Companies that can balance cost-effectiveness, quality assurance, and sustainability will be well-positioned to thrive in this competitive landscape. As the world becomes more environmentally conscious, the future of TIO2 manufacturing is likely to pivot towards cleaner, more efficient, and sustainable production methods.

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