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In a review published in 2022 in the journal Archives of Toxicologyresearchers found that the ingestion of E171 is a “a definite health risk for consumers and their progeny.” After reviewing dozens of in vivoex vivo and in vitro studies on the toxicity of E171, the researchers wrote that two facts must be noted: “First, reprotoxicity studies show that animals of both sexes are impacted by the toxicity of these nanoparticles, underlining the importance of conducting in vivo studies using both male and female animals. Second, human exposure begins in utero via maternal-fetal transfer and continues after birth by breastfeeding. Children are then chronically re-exposed due to their food preferences. To be relevant to the human in vivo situation, experimental studies should therefore consider nanoparticle exposure with respect to the age or life period of the studied population.”

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In the paint industry, titanium dioxide is extensively used as a pigment due to its high refractive index, which provides excellent hiding power and brightness. It is also known for its weather resistance and stability under various environmental conditions, making it suitable for both interior and exterior applications It is also known for its weather resistance and stability under various environmental conditions, making it suitable for both interior and exterior applications It is also known for its weather resistance and stability under various environmental conditions, making it suitable for both interior and exterior applications It is also known for its weather resistance and stability under various environmental conditions, making it suitable for both interior and exterior applicationsntr 606 titanium dioxide. Furthermore, it is used in plastics to enhance their strength and durability while also providing a natural color tone.

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