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In a 2016 study published in Scientifica (Cairo), Egyptian researchers examined the effects of titanium dioxide nanoparticles on the organs of mice by orally administering the food additive daily, for five days. The results showed that the exposure produced “mild to moderate changes in the cytoarchitecture of brain tissue in a time dependent manner.” Furthermore, “Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of Alzheimer’s disease.” The researchers wrote: “From these findings, “the present study concluded that TiO2NPs is genotoxic and mutagenic to brain tissue which in turn might lead to Alzheimer’s disease incidence.”

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TIO2, also known as titanium dioxide, is a white pigment that is widely used in various industries such as paints, plastics, paper, and cosmetics. Its unique properties make it an ideal choice for many applications. One of the most significant advantages of TIO2 is its high refractive index, which allows it to reflect light more efficiently than other pigments. This results in brighter and more vibrant colors that are highly sought after by consumers.

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