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For research published in Archives of Toxicology in 2020, scientists fed one group of mice a solution containing titanium dioxide for one month, and compared it to those that did not receive the additive. They found “the richness and evenness of gut microbiota were remarkably decreased and the gut microbial community compositions were significantly changed” in the titanium dioxide group when compared with the control group. The tests also revealed that the titanium dioxide exposure could cause locomotor dysfunction, or mobility issues “by elevating the excitement of enteric neurons, which might spread to the brain via gut-brain communication by vagal pathway.” The researchers concluded: “These findings provide valuable insights into the novel mechanism of TiO2NP-induced neurotoxicity. Understanding the microbiota-gut-brain axis will provide the foundation for potential therapeutic or prevention approaches against TiO2NP-induced gut and brain-related disorders.”

For research published in Archives of Toxicology in 2020, scientists fed one group of mice a solution containing titanium dioxide for one month, and compared it to those that did not receive the additive. They found “the richness and evenness of gut microbiota were remarkably decreased and the gut microbial community compositions were significantly changed” in the titanium dioxide group when compared with the control group. The tests also revealed that the titanium dioxide exposure could cause locomotor dysfunction, or mobility issues “by elevating the excitement of enteric neurons, which might spread to the brain via gut-brain communication by vagal pathway.” The researchers concluded: “These findings provide valuable insights into the novel mechanism of TiO2NP-induced neurotoxicity. Understanding the microbiota-gut-brain axis will provide the foundation for potential therapeutic or prevention approaches against TiO2NP-induced gut and brain-related disorders.”

Market Dynamics

Though the regulated use of titanium dioxide in food products is legal in the U.S. and Canada, it's banned in some other countries, notably throughout Europe. In May 2021, the European Food Safety Authority announced that titanium dioxide can no longer be considered safe as a food additive.

2. Mentality: the buyer has to prepare goods in advance, and the new order price is slightly less willing to purchase in bulk; Because the seller's inventory is small, the manufacturer has no willingness to reduce the price of sales.Trend: The load of titanium dioxide enterprises is stable, the willingness to ship at low prices is not strong, and the downstream buyers place orders in the early stage to establish inventory, and the short-term supplementary orders after the holiday are less. Anatase titanium dioxide due to the overall volume of the market supply side is less, the space for quotation negotiation is small, and the focus of new orders will move up. It is expected that the titanium dioxide market today just needs to be closed, and the market trading atmosphere is relatively light.

Infrared spectra were performed (from 400 to 4000 cm⁻¹) in vitamins@P25TiO₂NPs samples and the vitamins alone as controls, employing a Nicolet AVATAR 360 Fourier transform infrared spectrophotometer.

EFSA's evaluation is related to the risks of TiO₂ used as a food additive, not to other uses.

Now imagine the delicate skin on your face, on your children’s arms & legs. Each day un-knowingly, thinking we are doing the right thing, we slather them up with titanium dioxide in the form of sunscreen & send them out into the sun, all the while never knowing that once exposed to light titanium dioxide creates free radicals that are strong enough to damage steel roofing panels!!

≤0.3

CSPI’s Chemical Cuisine is the web’s definitive rating of the chemicals used to preserve foods and affect their taste, texture, or appearance. Besides titanium dioxide, the group recommends avoiding artificial sweeteners like aspartame, acesulfame potassium, and sucralose, as well as synthetic food dyes like Yellow 5 and Red 3. CSPI and others have recently asked the Food and Drug Administration to ban the latter dye in foods and ingested drugs because the FDA has already determined that it is a carcinogen unsafe for use in cosmetics.