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For research published in Archives of Toxicology in 2020, scientists fed one group of mice a solution containing titanium dioxide for one month, and compared it to those that did not receive the additive. They found “the richness and evenness of gut microbiota were remarkably decreased and the gut microbial community compositions were significantly changed” in the titanium dioxide group when compared with the control group. The tests also revealed that the titanium dioxide exposure could cause locomotor dysfunction, or mobility issues “by elevating the excitement of enteric neurons, which might spread to the brain via gut-brain communication by vagal pathway.” The researchers concluded: “These findings provide valuable insights into the novel mechanism of TiO2NP-induced neurotoxicity. Understanding the microbiota-gut-brain axis will provide the foundation for potential therapeutic or prevention approaches against TiO2NP-induced gut and brain-related disorders.”

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  • The production of barium sulfate involves several stages, including mining, beneficiation, and processing. The first step is to extract barium sulfate from the earth, which is typically done through underground or open-pit mining methods. Once the ore is extracted, it undergoes beneficiation to separate the barium sulfate from other impurities. This process may include washing, grinding, and flotation techniques.
  • Another significant advantage of wholesale titanium dioxide is its versatility. It can be used in a wide range of applications, including paints, plastics, coatings, textiles, and paper products. Its high refractive index and light scattering properties make it an excellent opacifier, which helps to create bright, vibrant colors and improve the overall appearance of products.