At the present JECFA meeting, the committee considered additional toxicological studies relevant to the safety assessment of the chemical that investigated its toxicokinetics, acute toxicity, short-term toxicity, long-term toxicity and carcinogenicity, genotoxicity, and reproductive and developmental toxicity, as well as special studies addressing its short-term initiation/promotion potential for colon cancer. The experts acknowledged that a large number of toxicological studies have been conducted using test materials, including nanoparticles, having size distributions and physico-chemical properties not comparable to real-world uses of titanium dioxide as a food additive. The studies on non-representative materials were evaluated by JECFA, but the committee concluded that such studies are not relevant to the safety assessment of the additive.
For instance, fluctuations in the price of zinc oxide and sulfur, key components in lithopone, directly impact the final price list For instance, fluctuations in the price of zinc oxide and sulfur, key components in lithopone, directly impact the final price list
, and Shanghai Kangle Chemical Co, and Shanghai Kangle Chemical Co
Moreover, Chinese manufacturers have been able to offer competitive prices, making their products attractive in the global market Moreover, Chinese manufacturers have been able to offer competitive prices, making their products attractive in the global market
Workers are equipped with protective gear and trained to handle potentially hazardous chemicals safely Workers are equipped with protective gear and trained to handle potentially hazardous chemicals safely
